- Projets
- biomedicale research
Projets
- Agronomy
- Environment
- Nutrition
- Biomedicale research
- Chimistry
- Medical informatics
- Integrative Biology
The LifeGrid platform unites all scientific stakeholders in Auvergne (public and private laboratories, businesses) by creating a regional information system that will organise, store and distribute the data obtained from research.
LifeGrid projects
Biomedicale research themes
LifeGrid biomedical projects cover an extensive activity sector ranging from bioinformatics to image processing and tissue, molecular and cellular engineering. The list of projects is presented below.
Information system for studying the genesis and development of cancer
The information system involves the high-speed processing of transcriptome data with a view to detecting genetic factors and understanding their roles in the development of cancer. This work needs to result in the creation of diagnosis and prognosis tools for these diseases.
M. BIGNON Yves-Jean
CENTRE JEAN PERRINInformation system for managing and searching for leukodystrophies
The main objective of the programme is to create the whole of the information system (tools and data) for studying leukodystrophies. This will enable the necessary tools for implementing the national PHRC obtained in 2005 to be set up in the short term. This work aims to determine the natural history and follow-up parameters of leukodystrophies associated with mutations of the PLP gene with a view to setting up therapeutic strategies at the INSERM-approved Clinical Investigation Centre (CIC).
Mme BOESPFLUG-TANGUY Odile
CHU Clermont-FerrandInformation system dedicated to the functioning of the CIC research platform
The objective is to develop an automated, reliable, effective and rapid acquisition system of the few thousand (or sometimes several tens of thousands) clinical and biological data generated by each study. Moreover, current clinical research approaches integrate more and more genome, transcriptome, metabolome and proteome approaches in physiological and physiopathological explorations or for understanding how medicines work in humans.
M. DUBRAY Claude
Centre d'Investigation CliniqueRegional biomedical information system
The project comprises 5 successive stages: updating the catalogue of useable data sources, selecting the useful bioinformatics data sources, defining and programming the structure of the regional database, creating a platform of transcriptome data processing algorithms and forming local structures for using this sytem.
ROMOND Pierre-Charles
Université d'Auvergne Clermont-FerrandDevelopment of an information system for using medical images to plan treatments by Monte Carlo GATE simulations on a computing grid
The project objective is to develop an information system for using medical images in the modelling of the dose deposit by Monte Carlo simulations on a grid. Two major aspects are to be developed for this project, taking account of the PCSV team’s developments over the last three years in partnership with the radiotherapy department at the Jean Perrin Centre:
1°) Optimised distribution of Monte Carlo grid computations. This involves: a) Optimum management of grid simulations to make significant computing time-savings. b) Transparent submission maintaining the confidentiality of medical data from GATE simulations for medical personnel and research stakeholders.
2°) Management, storage and secure access to medical images. This involves: a) Development of an interface between the PACS system and the computing grid b) Secure, optimum management of medical images on the grid for Monte Carlo GATE simulations
MAIGNE Lydia
LPC Clermont-FerrandLifeGrid, the regional information system